Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disorder that is caused when the motor nerve cells that control voluntary muscle movement gradually die resulting in paralysis and potentially death. It progresses at different rates in each individual, with the average time of survival being three years to five years from onset.

ALS strikes men and women equally between the ages of 40 and 70 years old, although it can start at an earlier or later age. Nationally, the incidence of ALS is 1 per 100,000 people with approximately 5,000 new cases diagnosed annually. It is not contagious nor is it generally an inherited disease, however 5 -10% of those who develop ALS has a family history of the disease. There is no known cause nor proven treatment for ALS, though researchers are exploring several viable theories. A number of clinical trials are currently underway with the hope that a successful treatment will be found. Until that time, many ALS symptoms can be successfully managed, enabling people to live their lives longer with dignity, while enjoying a greater quality of life.